Supplementary Figure 1 Mapping Statistics for all Hi-C samples.
Supplementary Figure 2 Previously reported translocations for cell lines in this study, as well as some novel ones, are evident in heatmaps of 2.5 MB resolution Hi-C data.
Supplementary Figure 3 (Part 1) Hi-C Heatmaps for chromosomes 1-5, per cell line, at a 250 kb bin resolution.
Supplementary Figure 3 (Part 2) Hi-C Heatmaps for chromosomes 6-11 , per cell line, at a 250 kb bin resolution
Supplementary Figure 3 (Part 3) Hi-C Heatmaps for chromosomes 12-X, per cell line, at a 250 kb bin resolution
Supplementary Figure 4 (Part 1) Cis Interaction heatmaps of 250kb-binned data, per chromosome, per cell line. Chromosomes 1-2
Supplementary Figure 4 (Part 2) Cis Interaction heatmaps of 250kb-binned data, per chromosome, per cell line. Chromosomes 3-6
Supplementary Figure 4 (Part 3) Cis Interaction heatmaps of 250kb-binned data, per chromosome, per cell line. Chromosomes 7-10
Supplementary Figure 4 (Part 4) Cis Interaction heatmaps of 250kb-binned data, per chromosome, per cell line. Chromosomes 11-13
Supplementary Figure 4 (Part 5) Cis Interaction heatmaps of 250kb-binned data, per chromosome, per cell line Chromosomes 14-X
Supplementary Figure 5 Compartment strength and similarity across cell lines.
Supplementary Figure 6 Plots of the 1st eigenvector for each chromosome, obtained from principal component analysis (PC1) of 250 kb-binned data
Supplementary Figure 7 Mathematical reconstruction of highly segmented genomic regions for compartment analysis.
Supplementary Figure 8 Analytical strategy to determine compartment change relevance in Prostate cancer progression.
Supplementary Figure 9 Examples of gene clusters
Supplementary Figure 10 The amyloid precursor protein (APP) – beta secretase 2 (BACE2) axis, located in chromosome 21 is a potential connection between transcriptional activity and compartment switching
Supplementary Table 2 Genes identified through DEigen 1 analysis (In at least 6 cancer cell lines OR in all 4 cancer cell lines represented in the axis).
Supplementary Table 3 Gene clusters that switch compartment identity with progression